| Player | Pos | Team | Status | GP | Pass Yds | Rush Yds | Rec Yds |
|---|---|---|---|---|---|---|---|
| Drake Maye | QB | NE | ACT | 21 | 5,222 | 628 | 2 |
| Sam Darnold | QB | SEA | ACT | 20 | 4,720 | 109 | - |
| Joshua Dobbs | QB | NE | ACT | 4 | 65 | -5 | - |
| Cam Akers | RB | SEA | ACT | 4 | 32 | 19 | - |
| Drew Lock | QB | SEA | ACT | 3 | 15 | -5 | - |
| Leonard Taylor III | DL | NE | ACT | 7 | - | - | - |
| K'Lavon Chaisson | LB | NE | ACT | 19 | - | - | - |
| Joshua Farmer | DL | NE | RES | 11 | - | - | - |
| Charles Cross | OL | SEA | ACT | 4 | - | - | - |
| Elijah Arroyo | TE | SEA | ACT | 13 | - | - | 179 |
| DeMarcus Lawrence | LB | SEA | ACT | 19 | - | - | - |
| Cooper Kupp | WR | SEA | ACT | 19 | - | - | 750 |
| Charles Woods | DB | NE | ACT | 11 | - | - | - |
| Milton Williams | DL | NE | ACT | 15 | - | - | - |
| Efton Chism III | WR | NE | INA | 10 | - | - | 95 |
| Mike Morris | DL | SEA | ACT | 13 | - | - | - |
| Jahlani Tavai | LB | NE | ACT | 16 | - | - | - |
| Jared Ivey | LB | SEA | INA | - | - | - | - |
| Vederian Lowe | OL | NE | ACT | 2 | - | - | - |
| Tory Horton | WR | SEA | RES | 8 | - | - | 161 |
| Chris Stoll | LS | SEA | ACT | 2 | - | - | - |
| George Holani | RB | SEA | ACT | 12 | - | 83 | 49 |
| Jaylinn Hawkins | DB | NE | ACT | 19 | - | - | - |
| Bradyn Swinson | LB | NE | INA | 1 | - | - | - |
| Boye Mafe | LB | SEA | ACT | 19 | - | - | - |
| Federico Maranges | OL | SEA | DEV | - | - | - | - |
| Jason Myers | K | SEA | ACT | 20 | - | - | - |
| Shaquill Griffin | DB | SEA | DEV | 1 | - | - | - |
| AJ Barner | TE | SEA | ACT | 20 | - | 16 | 586 |
| Patrick Johnson | LB | NE | DEV | 5 | - | - | - |
| CJ Dippre | TE | NE | INA | - | - | - | - |
| Olu Oluwatimi | OL | SEA | ACT | 1 | - | - | - |
| Craig Reynolds | RB | NE | DEV | 5 | - | 4 | - |
| Nick Kallerup | TE | SEA | INA | 4 | - | - | - |
| Thayer Munford Jr. | OL | NE | ACT | - | - | - | - |
| Robbie Ouzts | RB | SEA | INA | 5 | - | - | - |
| Otis Reese | LB | NE | DEV | - | - | - | - |
| Jack Westover | RB | NE | ACT | 5 | - | - | 8 |
| Antonio Gibson | RB | NE | RES | 5 | - | 106 | 6 |
| Andy Borregales | K | NE | ACT | 21 | - | - | - |
| Kenneth Walker III | RB | SEA | ACT | 20 | - | 1,340 | 386 |
| Stefon Diggs | WR | NE | ACT | 21 | - | - | 1,123 |
| Nehemiah Pritchett | DB | SEA | ACT | 9 | - | - | - |
| Richie Grant | DB | NE | DEV | 1 | - | - | - |
| Brock Lampe | RB | NE | RES | - | - | - | - |
| Kayshon Boutte | WR | NE | ACT | 18 | - | - | 719 |
| Garrett Bradbury | OL | NE | ACT | 5 | - | - | - |
| Amari Kight | OL | SEA | RES | - | - | - | - |
| Ben Brown | OL | NE | ACT | 3 | - | - | - |
| Bryce Cabeldue | OL | SEA | RES | 1 | - | - | - |